Hints and tips:
Related Special Reports
...It also wants a pivot in the biotech’s sales strategy for its Covid-19 shot, which is based on traditional vaccine technology, to target older people unnerved by rare side effects associated with mRNA jabs...
...The business is a rare recent success story in a sector battered by falling valuations and divestments from foreign investors....
...Biohaven, which was founded in 2013, specialises in drugs that target neurological diseases and rare disorders....
...The California-based pharmaceutical company agreed to the acquisition in December last year, winning a three-way race to add a new pipeline of drugs for rare autoimmune and inflammatory diseases....
...The results were particularly successful at finding rare genetic variants that confer a high risk of common disease....
...Horizon will give Amgen a stronger foothold in the lucrative rare disease drug space. Its thyroid eye disease treatment Tepezza pulled in $1.7bn in revenue last year....
...The pipeline includes drugs targeting rare inflammatory and autoimmune diseases as well as Horizon’s blockbuster treatment for thyroid eye disease, Tepezza....
...In the past, regulators have tended to focus their energies on drugmakers who try to corner the market by buying up lots of medicines that treat the same disease....
...The agreement gives Amgen access to Horizon’s pipeline of drugs for rare autoimmune and inflammatory diseases, including its blockbuster treatment for thyroid eye disease, Tepezza....
...“Elranatamab could potentially become a mega blockbuster,” said Chris Boshoff, chief development officer of Pfizer’s oncology and rare disease unit, referring to a drug candidate targeting multiple myeloma...
...The takeover would give Amgen access to Horizon’s pipeline of drugs for rare autoimmune and inflammatory diseases, including its blockbuster treatment Tepezza....
...The deal to acquire Alexion closed a year ago and in the second quarter, the rare disease business contributed $1.8bn in sales....
...The rare statement came less than two weeks after executives forecast subdued sales growth in the crucial period around Christmas, of below 8 per cent....
...Recordati’s three-year business plan unveiled earlier this year envisaged an expansion into the rare disease segment and the chair, who belongs to the founding Recordati family, said the deal “delivers on...
...He says he does not trust government and tries to avoid working with it (the CDC was a rare, and grudging, exception) because “it’s bureaucratic [and] politically driven”....
...The move is one of the boldest steps yet by chief executive Vas Narasimhan to focus Novartis on more lucrative drugs that include those targeting cancer and rare diseases....
...There were also questions by members about the potential risks posed by myocarditis, a rare condition associated with inflammation of the heart....
...The mRNA vaccines from Pfizer and Moderna have been associated with a rare heart inflammation, especially in younger men....
...“It’s either like Countryfile, where you’ve got some rare breed pigs and [people are] making artisan cheese, which is really nice but not exactly feeding the nation....
...Many are focusing on diseases where existing vaccines are not very effective, such as flu, or where there are none....
...Rather than throwing money around in a crisis, governments and multilateral groups should make it more profitable for companies to tackle developing country and rare diseases all the time....
...“And don’t we really need to on oncology, dementia and rare diseases?” he adds. “Lawyers are, by their nature, worriers,” he notes....
...He said Biogen could appeal against the recommendation but successful appeals were rare — about one in five — and it now looked unlikely the drug would make it over the line in Europe with the existing data...
...Pfizer has avoided many of the controversies that have affected rivals such as Moderna, Johnson & Johnson and AstraZeneca related to rare side effects such as myocarditis and blood clots....
...Even though vaccine mandates already exist for measles and other diseases, many health experts warn proposing mandates for Covid jabs could prove counterproductive....
International Edition