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Medical science
World-first trial of gene therapy to cure form of deafness begins
...Auditory neuropathy can be due to a variation in a single gene — known as the OTOF gene — which produces a protein called otoferlin....
October 11, 2023
Biotech
UK start-up Genomics raises £35mn for advanced genetic testing
...For example, he said about 15 to 20 per cent of women in the UK were at high risk for breast cancer because of a combination of genes, and so should be offered mammograms in their 40s, but could not be identified...
January 8, 2024
FT Live
Managing Operational Risk in M&A Transactions
Examining the value of business licensing and property tax in the deal cycle
Thursday, 20 JuneDigital Conference
Biotech
Japan’s development bank makes first UK life sciences investment
...Japan’s sovereign development bank is investing in UK life sciences for the first time with funding for 4Bio Capital, a UK venture fund that backs advanced treatments such as cell and gene therapies....
January 4, 2024
News updates from April 26: US PCE rises 2.7% in March; Anglo American rejects BHP takeover bid
US regulators approve Pfizer’s gene therapy for rare blood clotting disorder
...Pfizer is gearing up to launch its first-ever gene therapy at a list price of $3.5mn, after US regulators approved the treatment for a rare blood clotting disorder on Friday....
April 26, 2024
News updates from February 7: Netanyahu rejects Hamas ceasefire demand, Disney unveils $3bn buyback
European parliament gives go-ahead for farmers to use gene editing on crops
...EU lawmakers have voted to approve a controversial law that will make it easier for farmers to use gene editing to improve the resilience of crops....
February 7, 2024
Biotech
Gene-editing pioneer calls for big investment in Crispr technology
...gene or tweaking it to change its function....
March 21, 2024
FT Live
US Pharma and Biotech Summit
Strategies for innovation, pricing and access
Thursday, 16 MayNew York, NY, USA
News updates from December 8: US adds 199,000 jobs in November, UK competition watchdog examining Microsoft-OpenAI ties
US drug regulator approves Crispr gene editing therapy
...The UK approved Casgevy in November, making it the first country to greenlight a therapy based on Crispr gene editing....
December 8, 2023
Medical science
Scientists use Crispr gene editing to treat hereditary disorder
...“We used a single infusion over two to four hours — and the gene editing takes place inside the liver,” he said....
January 31, 2024
News updates from November 16: Oil prices hit 4-month low, Wirecard hacker sentenced to 80 months in prison
UK approves Crispr gene editing therapy in global first
...Crispr is a flexible and efficient gene editing tool based on the bacterial immune system....
November 16, 2023
Drug prices
Rare genetic disease therapy becomes world’s most expensive drug at $4.25mn
...Lenmeldy works by inserting a genetically modified version of the gene that causes MLD in a patient’s blood stem cells and delivering it via an infusion....
March 20, 2024
Special ReportFuture of Healthcare
New medicine could prevent disease before it begins — but at a cost
...“We’re at the stage where we have target organisms, and even target genes, that we know are contributing to a wide range of clinical outcomes,” says Susan Lynch, head of San Francisco’s Benioff Center for...
May 3, 2024
Special ReportHealth and Climate Change
Climate change risks fuelling antibiotic-resistant ‘superbugs’
...Wastewater is a “reservoir for antibiotic-resistance genes” (ARGs), according to the environmental research journal’s paper....
April 29, 2024
Medical science
Brain organoids target rare neurological disorder
...The scientists then targeted the action of a gene known as CACNA1C, which causes a mutation fundamental to Timothy syndrome....
April 24, 2024
News in-depthNews in-depth3 min
Crispr gene editing technology could transform medicine | FT Tech
...But the UK has just become the first country to approve a therapy based on Crispr gene editing, authorising a treatment for sickle cell disease and beta thalassemia....
December 5, 2023
Mergers & Acquisitions
EU wrong to block Illumina’s $8bn takeover of Grail, says court adviser
...A senior EU court adviser has said the European Commission was wrong to block gene sequencing group Illumina’s $8bn acquisition of Grail and that the decision should be scrapped....
March 21, 2024
FT Live
Funding Biopharma Innovation
Strategies for investing in drug development and commercialization
Wednesday, 26 June345 Park Avenue South, New York, NY, USA
Special ReportFuture of Healthcare
New medical technologies are here. But when will they reach your GP?
...“One reason why we don’t use genome sequencing is that we don’t know enough about gene function to know what [a particular] sequence actually means for a patient and their treatment.”...
May 14, 2024
Anjana Ahuja
The EU risks losing out on farming’s genomic reboot
...“It is a great testament to their ingenuity, combined with the acceptance that something needs to be done quickly, that these early developers of gene-editing are not in the resource-rich [global] north,...
January 31, 2024
InterviewBristol-Myers Squibb Co
Bristol Myers Squibb drafts contingency plans for US restrictions on Chinese pharma
...WuXi AppTec is also widely used by cell and gene therapy drugmakers....
April 25, 2024
Camilla Cavendish
Science is closing in on the frailties of old age
...It seems to work by suppressing the mTOR complex, a set of genes that regulate metabolism....
April 26, 2024
Medical science
UK approves Crispr gene editing therapy in global first
...The UK has become the first country to approve a therapy based on Crispr gene editing, with the regulator authorising a treatment for sickle cell disease and beta thalassaemia....
November 16, 2023
ReviewScience books
How Life Works — why there’s more to it all than DNA
...One clue was that when the Human Genome Project sequenced a human’s DNA in 2003, scientists were shocked to find only some 20,000 genes for proteins, the same as a much less complex worm....
February 2, 2024
Kate Burgess
How to invest in biotech
...It has a concentrated portfolio of about 20 cell and gene therapy start-ups with treatments in early and late stage trials....
May 2, 2024
Europe Express
Why the EU’s climate chief says the green agenda must endure Premium content
...Japanese professor Hiroshi Ezura, who created the world’s first commercially sold gene-edited fruit, a tomato that can reduce blood pressure, visited Brussels last week to convince lawmakers to press ahead...
January 29, 2024
Scientific research
AI explores ‘dark genome’ to shed light on cancer growth
...“They end up being clustered around genes that are altered in cancer in a variety of different ways, providing the first glimpse that these sequences may be key to tumour development,” he said....
March 13, 2024
Highlights from the New Hampshire primary: Trump wins, Haley vows to press on
Comment: New Hampshire likes to surprise
...New Hampshire likes to surprise, as we’ve seen so many times in the past — there has been a strange range of winners there from Bernie Sanders to Pat Buchanan (even Gene McCarthy nearly bested LBJ there)...
January 23, 2024

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