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...Find has helped support the development and application in South Africa of GeneXpert, a test that confirms TB and the presence of the strain resistant to the drug rifampicin....
...It is not known how the disease spreads but it can be treated with the combined antibiotics rifampicin and streptomycin. Early diagnosis and treatment are the only ways to prevent disability....
...Within two hours a doctor will know if the patient has TB and if that form of TB is resistant to rifampicin (RIF), one of the leading TB antibiotics. Xpert has many advantages....
...It is sometimes combined with rifampicin, a drug used against active TB, though this can reduce the efficacy of contraceptives if they are being taken....
...Sildenafil (Viagra) can affect your vision, making everything look blue; the antibiotic rifampicin may dye urine orange....
...Other trials are examining improved efficacy by raising the dose of rifampicin, a backbone of existing therapy....
...Blood, beetroot and the anti-TB drug rifampicin dye urine red; vitamin B tablets produce a wild shade of yellow; the antidepressant amitriptyline can turn urine blue....
...The test’s sensitivity to TB that is resistant to an important antibiotic – Rifampicin – was 95.1 per cent. Ordinary smears cannot detect antibiotic resistance....
...The factory makes medicines using combinations of rifampicin, an antibiotic used to treat tuberculosis that is widely used in developing countries....
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