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Danish biotech group Zealand Pharma is developing an alternative obesity treatment to compete with big rivals
...Large pharmaceutical companies were sitting on significant cash piles and wanted to invest to fill drug pipelines before patents on some major blockbusters expired by the end of the decade, he added....
...“We aim to not just alleviate disease symptoms, but to address the root causes of heart failure and restore the normal functioning of the heart,” said Thomas Thum, Cardior’s co-founder....
...The US pharmaceutical company — whose shares are up 130 per cent over the past year and is now a top-10 S&P 500 stock — chose the week of the Oscars to launch an advert called “Big Night”....
...The push into prescriptions and drug delivery is unusual for a pharmaceutical manufacturer, pitting Eli Lilly against pharmacies such as CVS and Walgreens....
...therapies based on Crispr gene-editing globally is “unrealistic” and the sector needs heavy investment to make the technology, which could transform treatment of diseases, accessible to all, according to its co-discoverer...
Breakthrough medicine will now be subject to further review by committee of independent experts
...Eli Lilly was once considered something of an also-ran in the pharmaceutical industry....
...Pharmaceutical companies must replenish their drugs pipeline before exclusivity rights on top-selling products expire....
...Eli Lilly is racing to secure the services of outsourcers to boost production of its obesity drug Zepbound, as the US pharmaceutical group rolls out its rival to Danish group Novo Nordisk’s blockbuster appetite...
...Her comments highlight difficulties in capitalising fully on the rising pace of scientific discoveries, boosted by artificial intelligence, as growing geopolitical tensions hinder international co-operation...
...“The presence of interferon-γ could be used to diagnose long Covid in some patients,” said Benjamin Krishna, co-author of the paper and a Cambridge university researcher....
...Orchard, a UK-based biotech that was recently bought by Japanese pharmaceutical group Kyowa Kirin, argued that the lack of other treatments for MLD justified the price....
...Another official said: “What we want to do is give WHO a co-ordinating role but it should not mean that [data] cannot be shared through established systems. It is up to the member states.”...
...His efforts included a conversation with an unnamed “board member I knew at BI” and approaches to KKR co-founder Henry Kravis, its co-CEO Joseph Bae and Axel Springer’s Döpfner....
...A co-founder of activist fund ValueAct, Ubben said last year that his three-year-old Inclusive Capital was being wound down. He is also on the board of US oil major ExxonMobil....
...“Instead of chasing variants, we are predicting them,” said Ariane Gomes, a Baseimmune co-founder. “This is part of why we say our vaccines last for longer.”...
...Beyond these price pressures, pharmaceutical companies have other reasons to worry about their reliance on animal testing....
...“What is most important is that it kills antibiotic-resistant strains in animals,” said Yury Polikanov, co-author of the research and an associate professor of biological sciences at the University of Illinois...
...Cheaper valuations have finally drawn cash-rich pharmaceutical makers back to biotechs. Their aim, as always, is to replenish their drug pipelines affordably. Relief is sorely needed....
...High demand for weight-loss drugs has helped Novo Nordisk become Europe’s largest company by market capitalisation, while Eli Lilly overtook Johnson & Johnson as the world’s largest pharmaceutical company...
Mounjaro has achieved 22.5 per cent loss of body weight in trials
...The treatment proved simple, convenient and precisely targeted, said Padmalal Gurugama, co-author of the paper and a consultant in clinical immunology and allergy at Cambridge University Hospital....
...New treatments being developed for Alzheimer’s offered the best hope yet of ending “the devastation this condition inflicts on people and society”, said Hilary Evans, co-chair of the Dame Barbara Windsor...
US group relies on some of the sites being purchased by competitor to produce its own treatments
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