Hints and tips:
...This month the company appointed Chris Smith, chief executive of Nasdaq-listed Ortho Clinical Diagnostics to chair the board, and David Berry, general partner at healthcare venture capital firm Flagship...
...In a phase 2b trial of patients with moderate to severe ulcerative colitis, a type of IBD, it improved clinical remission by 36 per cent in 56 weeks, compared with placebo....
...According to the NHS, 6mn people are now on the waiting list for elective care — all non-urgent medical services ranging from diagnostic tests and scans, to surgery and cancer treatment — up from 4.4mn prior...
...Diagnostic tests — brain scans and/or lumbar punctures — are required to determine eligibility for treatment. And the drug is not a simple chemical but an antibody, expensive to develop and produce....
...A few other amyloid-busting drugs, which may work better than aducanumab, are in clinical trials....
...Wise also pointed to Ortho Clinical Diagnostics, which Carlyle spun out of US drugmaker Johnson & Johnson in 2014....
...But if this drug is approved for the condition, he said oncologists should be using the diagnostic to select patients right for the medicine....
...Desperate to keep the condition at bay, the former IT executive signed up for the clinical trial of Biogen’s experimental Alzheimer’s drug, aducanumab....
...Stanley Erck, Novavax’s chief executive, said it was the “first vaccine to demonstrate not only high clinical efficacy against Covid-19 but also significant clinical efficacy against both the rapidly emerging...
...Of these, the bulk was done by just two companies: Quest Diagnostics and Laboratory Corporation of America....
...PCR (polymerase chain reaction) tests, the gold standard of diagnostic sensitivity, cannot provide results in real time....
...Clinical Diagnostics....
...Although they are down for the week, Steris and Quest Diagnostics have notably outperformed the broader market....
...Growing demand for genomic information and applications saw diagnostics company Illumina soar past analysts’ expectations in the second quarter and boost its forecast for full-year sales growth and earnings...
...Last month its scientists published results of an early clinical trial in Proceedings of the National Academy of Sciences, a leading scientific journal....
...The study found that oncologists could use a genetic test called Oncotype DX — made by Genomic Health, a Californian diagnostics company — to predict accurately which women would benefit from chemotherapy...
...Pharmaceutical companies spent tens of billions of dollars on clinical trials to test new drugs each year....
...Guardant has also signed deals with other large drugmakers like Merck and AstraZeneca, which want to use the test in their clinical trials....
...The value of the diagnostics, physical rehabilitation and surgery segment alone is set to pass $14bn next year....
...In December, hackers infiltrated Quest Diagnostics, which boasts the world’s largest clinical lab database, and gained access to 34,000 patient records, including laboratory results....
...Public health capacity — including human and animal disease surveillance — must be improved, as well as global efforts to accelerate R&D of vaccines, drugs and diagnostics....
...Unless we have the proper tools — new drugs and diagnostics — we won’t go anywhere. We need to empower people in the community to have a massive scale-up of treatment....
...Just as important could be advances in diagnostic technology leading to earlier, more accurate detection....
...“Without adequate business scale, clinical lab services are an unappealing target market,” said analysts at Kalorama Information, a medical market research group, in a report earlier this month....
...Six clinical trials of the technology are under way with a target to secure US regulatory approval next year....
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