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...AstraZeneca set up a vaccines and immune therapies unit after it partnered with the University of Oxford to develop a Covid-19 vaccine....
...T-cells are a type of white blood cell that play a disease-fighting role in the human immune system....
...This primes the body to recognise the virus if infected and make an immune response....
...“They can now be approached in a focused way without collateral damage to the rest of the immune system....
...But fewer groups focus on the antigen used to elicit an immune response in those receiving a vaccine, said Baseimmune....
...“It was one of the most epic episodes ever in pharmaceuticals history: you got an accelerated approval of a product that didn’t have a completed phase 3 trial....
...Belkaid is a specialist in the relationship between microbes and the immune system. She was previously director of the US National Institutes of Health Center for Human Immunology....
...It is used clinically to damp infections in people whose immune systems have been compromised by chronic granulomatous disease, a genetic disorder that makes people susceptible to dangerous bacterial and...
...It is used against a rare chronic immune disorder called myasthenia gravis, which causes muscle weakness....
...Other companies are developing therapies based on Crispr, which is based on the bacterial immune system....
...This is implicated in outsize immune responses such as those which cause IBD. Crohn’s disease and ulcerative colitis are the two commonest forms....
...The Medicines and Healthcare products Regulatory Agency has approved the therapy, called Casgevy, which was developed by Vertex Pharmaceuticals and Crispr Therapeutics....
...Ireland’s corporation tax receipts bounced back strongly in November after three months of falls, alleviating fears that a bonanza from international technology and pharmaceutical companies in the country...
...Given that many cancer therapies weaken the immune system, making patients more susceptible to infections, this is to some extent to be expected....
...Also in the frame are the technology and pharmaceutical sectors. Their wealth of intellectual property makes them particularly adept at shifting profits....
...Infection reawakens memories of these pathogens, stimulating the immune system to bite back at a known foe....
...Figuring out how to design a vaccine that can teach immune cells how to recognise and combat tumours could become the next big thing in the $200bn a year oncology drug market....
...Teresa Graham, chief of Roche’s pharmaceutical division, said more patients suffered from diseases of the immune system than from cancer, and the current drugs did not serve them well....
...Crispr is a flexible and efficient gene editing tool based on the bacterial immune system....
...Moderna’s flu vaccine elicited a better immune response than existing jabs in a late-stage trial, paving the way for the Boston-based biotech company to enter the $6bn annual market....
...The Covid vaccines developed during the pandemic became the first shots to use messenger RNA technology, which uses a genetic code to teach the immune system to recognise the virus....
...The pill, taken in combination with 5-FU, the world’s most widely used chemotherapy treatment, attempts not only to kill off malignant cells as many therapies do, but also to stimulate the body’s immune...
...BioNTech, the German company that was to collaborate with pharmaceuticals group Pfizer on developing a Covid vaccine, quickly recruited Karikó as research vice-president....
...AstraZeneca has signed a deal worth up to $247mn with Absci Corporation of the US to design an antibody to fight cancer, the latest tie-up in fast-expanding efforts to use artificial intelligence for drug...
...The chance of developing the condition increases with age, as people’s immune systems become less robust....
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