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...Mutations in the OTOF gene can be identified by genetic testing. However, Bance said it was a condition often missed when newborn babies were screened for potential hearing problems....
...The University of Oxford spinout is pushing genetic testing beyond the search for individual genes, looking at how combinations of genes increase people’s likelihood of developing diseases such as cancer...
...He said that about a third of all approvals by the US drugs regulator were for advanced therapies, including the recent approval of the first treatment that uses Crispr gene-editing, for sickle cell disease...
...Her institute is also assessing Crispr applications in agriculture, including tackling climate change by removing genes in the cow microbiome that are responsible for methane emissions....
...The FDA approved Casgevy, a treatment developed by Vertex Pharmaceuticals and Crispr Therapeutics. The FDA’s approval includes Casgevy and Bluebird Bio’s therapy called Lyfgenia....
...The technology was discovered in 2012 by Jennifer Doudna and Emmanuelle Charpentier, who won a Nobel Prize for their work in 2020....
...Crispr is a flexible and efficient gene editing tool based on the bacterial immune system....
...Lenmeldy works by inserting a genetically modified version of the gene that causes MLD in a patient’s blood stem cells and delivering it via an infusion....
...The decision to block the deal between the world’s biggest gene sequencing group and cancer screening start-up Grail was made in September 2022 after a referral by France and other member states....
...But the UK has just become the first country to approve a therapy based on Crispr gene editing, authorising a treatment for sickle cell disease and beta thalassemia....
...The gene-edited sorghum project is inspired by nature — specifically by wild varieties of the staple that carry genetic mutations conferring resistance to Striga....
...The Medicines and Healthcare products Regulatory Agency has approved the therapy, called Casgevy, which was developed by Vertex Pharmaceuticals and Crispr Therapeutics....
...This isn’t clockwork: the complex system moves towards the “right” stable state by many possible paths, governed by interactions at many levels....
...Prof Ezura said the so-called NGTs were far quicker and worked with existing genes rather than introducing others....
...“While still at an early stage, this research demonstrates how some cancers could be diagnosed earlier by detecting tumour-specific changes in cells collected from blood samples,” said Hattie Brooks, the...
...Yet many scientists still lack the depth of insight into plant genomes needed for confident gene-editing decisions....
...The licensee is likely to be Constructive Bio, an LMB spinout founded in 2022 with $15mn seed funding to commercialise the research by Chin’s team....
...Gene Simmons, bassist and co-founder of Kiss, said there were various plans in development, including the virtual concert, a biopic and a Kiss-themed “experience”....
...editing in introducing genetic resistance to disease caused by influenza in farmed animals”....
...Gene Munster at Deepwater Asset Management said he was surprised by Apple’s decision to settle the case, given companies commonly offer commentary on market trends....
...— representing about half of its parliamentary caucus — went on to say they “fully supported” Mützenich’s suggestion, and that seeking to negotiate a peaceful outcome with Russia was in the movement’s “genes...
...Gene-editing pioneer Jennifer Doudna meanwhile called for therapies to be made available for all through increased investment in Crispr technology....
...Gene Munster, a partner at the technology investor Deepwater Asset Management, concurred. Arm “is part of the AI story....
...This is despite lacklustre sales of the Oxford/AstraZeneca Covid-19 vaccine manufactured by the company....
...What at first seems accidental turns out to have been an assassination by a foreign power, using remote gene-editing technologies....
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